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Desipramine
Information about Desipramine: Includes the warnings, side effects, precautions and drug interactions.
IMPORTANT NOTE | TITLE | HOW TO PRONOUNCE | COMMON BRAND NAMES | USES | OTHER USES | HOW TO TAKE | SIDE EFFECTS | PRECAUTIONS | DRUG INTERACTIONS | OVERDOSE | NOTES | MISSED DOSE | STORAGE
IMPORTANT NOTE The following information is intended to
supplement, not substitute for, the expertise and judgment of your physician,
pharmacist or other healthcare professional. It should not be construed to
indicate that use of the drug is safe, appropriate, or effective for you.
Consult your healthcare professional before using this drug.
TITLE TRICYCLIC ANTIDEPRESSANTS - ORAL, INJECTION
USES This medication is used to treat depression,
obsessive-compulsive disorders, and bed-wetting in children over 6 years of age
(enuresis).
OTHER USES This medication may also be used to treat nerve pain,
sleeping problems (insomnia), and has other uses as determined by your doctor.
HOW TO TAKE Use this as prescribed. Try to use each dose at the same
time(s) each day so you remember to routinely use it. It may take 2 to 3 weeks
before the full benefit of this medication becomes apparent. Do not stop using
this medication without your doctor's approval. Nausea, headache or fatigue can
occur if the drug is suddenly stopped.
SIDE EFFECTS May cause drowsiness, dizziness, increased sun
sensitivity or blurred vision. May initially cause dizziness and lightheadedness
when rising too quickly from a sitting or lying position. Other side effects
include heartburn, loss of appetite, dry mouth, strange taste in mouth, anxiety,
restlessness or sweating. If any side effects persist or worsen, notify your
doctor. Report promptly: chest pain, rapid or irregular heartbeat, difficulty
urinating, nightmares, ringing in the ears, excessive drowsiness, uncoordinated
movements, fainting. Taking this medication at bedtime may help minimize side
effects. Talk to your doctor about this. In the unlikely event you have an
allergic reaction to this drug, seek medical attention immediately. Symptoms of
an allergic reaction include: rash, itching, swelling, dizziness, trouble
breathing. If you notice other effects not listed above, contact your doctor or
pharmacist.
PRECAUTIONS Before using this drug tell your doctor your medical
history, especially of: glaucoma, prostate problems, decreased urine output,
thyroid disease, breathing problems, seizure problems, alcohol use, heart
disease, mental/emotional problems, liver or kidney disease, any drug allergies.
Use caution when engaging in tasks requiring alertness such as driving or
operating machinery. Limit alcohol consumption as it may increase the drowsiness
and dizziness effects of this drug. Limit exposure to hot weather as it may lead
to heat stroke. Though uncommon, depression itself can lead to thoughts or
attempts of suicide. Tell your doctor immediately if you have any suicidal
thoughts, or other mental/mood changes. Keep all medical appointments so your
doctor can monitor your progress closely. Caution is advised when using this
drug in the elderly, because they may be more sensitive to the effects of the
drug (e.g., confusion may occur or worsen). This drug should be used during
pregnancy only if clearly needed. Discuss the risks and benefits with your
doctor. This drug may be excreted into breast milk. The effects on the infant
are not known at this time. Consult your doctor before breast-feeding.
DRUG INTERACTIONS Inform your doctor about the medicines you take,
especially if you take: clonidine, guanadrel, guanethidine, MAO inhibitors
(e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine),
cimetidine, SSRIs (e.g., fluoxetine, sertraline), warfarin, carbamazepine,
certain diet pills (e.g., phentermine, fenfluramine), adrenaline-type drugs
(e.g., dopamine, ephedrine, epinephrine, pseudoephedrine, phenylephrine,
isoproterenol- some of which may be found in cough-and-cold or asthma products),
narcotic pain medications (e.g., codeine), cisapride, St John's wort, heart
rhythm drugs (e.g., quinidine, flecainide, propafenone), phenothiazines (e.g.,
chlorpromazine), any other prescription or nonprescription drugs you take. Do
not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE If overdose is suspected, contact your local poison
control center or emergency room immediately. US residents can call the US
national poison hotline at 1-800-222-1222. Canadian residents should call their
local poison control center directly. Symptoms of overdose may include
agitation, confusion, hallucinations, fever, irregular movement of the eyes,
seizures, change in amount of urine, dry mouth or nose, constipation, large
pupils, drowsiness, slow or shallow breathing, dizziness, unconsciousness,
unusually fast or slow heartbeat, or flushing..
NOTES Do not allow anyone else to use this medication.
MISSED DOSE If you miss a dose and are taking more than 1 daily: do
not take it if it is almost time for the next dose, instead, skip the missed
dose and resume your usual dosing schedule. If you take it once daily at
bedtime, do not take it the following morning. Call your doctor. Do not double
the dose to catch up.
STORAGE Store at room temperature away from moisture and
sunlight. Do not store in the bathroom. Do not freeze liquid forms of this
medication.
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